Revisión sistemática y meta-análisis de fiabilidad de los instrumentos de evaluación para la Demencia Frontotemporal
Abstract
Introduction: Frontotemporal dementia (FTD) is a progressive form of dementia that affects behavior and cognitive function. Assessing knowledge about this disease is crucial for proper diagnosis and treatment. Various assessment instruments have been adapted and validated in different cultural contexts, but their reliability varies. Objective: To analyze the scientific literature on assessment tools used to measure knowledge and progression of FTD, with the aim of conducting a meta-analysis of reliability, focusing on Cronbach's alpha in different cultural adaptations and contexts. Methodology: Four scientific databases (Web of Science, Scopus, PsycINFO, and PubMed) were reviewed to gather information on the reliability (Cronbach’s alpha) of FTD assessment tools in diverse populations. Data on the population, validation method, cultural context, and internal consistency (Cronbach's alpha) of each instrument were collected. Results: The findings showed that the internal consistency of the instruments varies by context. For instance, the FTDKS scored a Cronbach’s alpha of .846 in the United States, .740 in Spanish-speaking countries, and .800 in Poland. The FTD-FRS showed an exceptional alpha of .975 in Brazil. The meta-analysis model (nStudies = 3) demonstrated an overall reliability of .85 (CIα = .80-.90). Conclusion: FTD assessment tools exhibit reliability variations depending on the cultural context. Proper adaptations are essential to improve their effectiveness in assessing knowledge about the disease, thereby facilitating better diagnosis and patient care.
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References
- Bang J, Spina S, Miller BL. Frontotemporal dementia. Lancet. 2015; 24;386(10004):1672–82. https://doi.org/10.1016/S0140-6736(15)00461-4. DOI: https://doi.org/10.1016/S0140-6736(15)00461-4
- Bott NT, Radke A, Stephens ML, Kramer JH. Frontotemporal dementia: diagnosis, deficits and management. Neurodegener Dis Manag. 2014;4(6):439–54. https://doi.org/10.2217/nmt.14.34. DOI: https://doi.org/10.2217/nmt.14.34
- Young JJ, Lavakumar M, Tampi D, Balachandran S, Tampi RR. Frontotemporal dementia: latest evidence and clinical implications. Ther Adv Psychopharmacol. 2018 Jan;8(1):33–48. https://doi.org/10.1177/2045125317739818. DOI: https://doi.org/10.1177/2045125317739818
- Hogan DB, Jetté N, Fiest KM, Roberts JI, Pearson D, Smith EE. The prevalence and incidence of frontotemporal dementia: a systematic review. Can J Neurol Sci. 2016 Apr;43(Suppl 1). https://doi.org/10.1017/cjn.2016.25 DOI: https://doi.org/10.1017/cjn.2016.25
- Mendez MF, Shapira JS, McMurtray A, Licht E, Miller BL. Accuracy of the clinical evaluation for frontotemporal dementia. Arch Neurol. 2007;64(6):830–5. https://doi.org/10.1001/archneur.64.6.830. DOI: https://doi.org/10.1001/archneur.64.6.830
- Leroy M, Bertoux M, Skrobala E, Mode E, Adnet-Bonte C, Le Ber I. Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network. Alz Res Therapy. 2021;13:19. https://doi.org/10.1186/s13195-020-00753-9 DOI: https://doi.org/10.1186/s13195-020-00753-9
- Cahill S, Pierce M, Werner P, Darley A, Bobersky A. A systematic review of the public’s knowledge and understanding of Alzheimer’s disease and dementia. Alzheimer Dis Assoc Disord. 2015;29(3):255–75. https://doi.org/10.1097/WAD.0000000000000102. DOI: https://doi.org/10.1097/WAD.0000000000000102
- Leszko M, Carpenter BD. Reliability and validity of the Polish version of the Alzheimer’s disease knowledge scale. Dement Geriatr Cogn Disord. 2021;50(1):51–9. https://doi.org/10.1159/000514872. DOI: https://doi.org/10.1159/000514872
- Lüdecke D, von dem Knesebeck O, Kofahl C. Public knowledge about dementia in Germany – results of a population survey. Int J Public Health. 2016;61(1):9–16. https://doi.org/10.1007/s00038-015-0703-x DOI: https://doi.org/10.1007/s00038-015-0703-x
- Pose M, Cetkovich M, Gleichgerrcht E, Ibáñez A, Torralva T, Manes F. The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry. 2013;25(2):159–67. https://doi.org/10.3109/09540261.2013.769939. DOI: https://doi.org/10.3109/09540261.2013.769939
- Finger EC. Frontotemporal dementias. Continuum. 2016 Apr;22(2 Dementia):464–89. https://doi.org/10.1212/CON.0000000000000300 DOI: https://doi.org/10.1212/CON.0000000000000300
- Caceres BA, Frank MO, Jun J, Martelly MT, Sadarangani T, de Sales PC. Family caregivers of patients with frontotemporal dementia: an integrative review. Int J Nurs Stud. 2016 Mar;55:71–84. https://doi.org/10.1016/j.ijnurstu.2015.10.016. DOI: https://doi.org/10.1016/j.ijnurstu.2015.10.016
- O’Keeffe FM, Murray B, Coen RF, Dockree PM, Bellgrove MA, Garavan H. Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy. Brain. 2007 Mar;130(Pt 3):753–64. https://doi.org/10.1093/brain/awl367 DOI: https://doi.org/10.1093/brain/awl367
- Ducharme S, Dols A, Laforce R, Devenney E, Kumfor F, van den Stock J. Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders. Brain. 2020;1;143(6):1632–50. https://doi.org/10.1093/brain/awaa018. DOI: https://doi.org/10.1093/brain/awaa018
- Wynn MJ, Carpenter BD. Frontotemporal dementia knowledge scale: development and preliminary psychometric properties. Alzheimer Dis Assoc Disord. 2020;34(1):59–65. https://doi.org/10.1097/WAD.0000000000000344. DOI: https://doi.org/10.1097/WAD.0000000000000344
- Leszko M, Zając-Lamparska L, Trempala J. Aging in Poland. Gerontologist. 2015;55(5):707–15. https://doi.org/10.1093/geront/gnu171. DOI: https://doi.org/10.1093/geront/gnu171
- Carvalho A, Rea IM, Parimon T, Cusack BJ. Physical activity and cognitive function in individuals over 60 years of age: A systematic review. Clinical Interventions in Aging. 2014;9:661–82. https://doi.org/10.2147/CIA.S55520. DOI: https://doi.org/10.2147/CIA.S55520
- Casaletto KB, Rentería MA, Pa J, Tom SE, Harrati A, Armstrong NM, Rajan KB, Mungas D, Walters S, Kramer J, Zahodne LB. Late-life physical and cognitive activities independently contribute to brain and cognitive resilience. Journal of Alzheimer’s Disease: JAD. 2020;74(1):363–76. https://doi.org/10.3233/jad-191114. DOI: https://doi.org/10.3233/JAD-191114
- Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021; 372. https://doi.org/10.1136/bmj.n71. DOI: https://doi.org/10.1136/bmj.n71
- Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. PLoS Med. 2021;18(3):e1003583. https://doi.org/10.1371/journal.pmed.1003583. DOI: https://doi.org/10.1371/journal.pmed.1003583
- Rethlefsen ML, Kirtley S, Waffenschmidt S, Ayala AP, Moher D, Page MJ, Koffel JB; PRISMA-S Group. PRISMA-S: an extension to the PRISMA Statement for Reporting Literature Searches in Systematic Reviews. Syst Rev. 2021;10(1):39. https://doi.org/10.1186/s13643-020-01542-z. DOI: https://doi.org/10.1186/s13643-020-01542-z
- Ouzzani, M., Hammady, H., Fedorowicz, Z. et al. Rayyan—a web and mobile app for systematic reviews. Syst Rev 5, 210 (2016). https://doi.org/10.1186/s13643-016-0384-4 DOI: https://doi.org/10.1186/s13643-016-0384-4
- Cho E. Neither Cronbach’s Alpha nor McDonald’s Omega: A Commentary on Sijtsma and Pfadt. Psychometrika. 2021;86:877–86. https://doi.org/10.1007/s11336-021-09801-1. DOI: https://doi.org/10.1007/s11336-021-09801-1
- Barchard KA, Hakstian AR. The Effects of Sampling Model on Inference with Coefficient Alpha. Educ Psychol Meas. 1997;57(6):893–905. https://doi.org/10.1177/0013164497057006001. DOI: https://doi.org/10.1177/0013164497057006001
- Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539–58. https://doi.org/10.1002/sim.1186 DOI: https://doi.org/10.1002/sim.1186
- Wynn JC, Carpenter BD. Frontotemporal Dementia Knowledge Scale: Development and preliminary psychometric properties. Alzheimer Dis Assoc Disord. 2020;34(1):45–52. https://doi.org/10.1097/WAD.0000000000000344 DOI: https://doi.org/10.1097/WAD.0000000000000344
- Magrath-Guimet M, Martínez-Acosta F, Romero-López A. Spanish version of the Frontotemporal Dementia Knowledge Scale: Adaptation and validation. Arq Neuropsiquiatr. 2022;80(2):134–44. https://doi.org/10.1590/0004-282X-ANP-2020-0550 DOI: https://doi.org/10.1590/0004-282x-anp-2020-0550
- Turró-Garriga O, Bruna-Bosch X, Gutiérrez-Villarreal M. Adaptation and validation of a Spanish-language version of the Frontotemporal Dementia Rating Scale (FTD-FRS). Neurologia. 2017;32(6):386–94. https://doi.org/10.1016/j.nrl.2015.12.004 DOI: https://doi.org/10.1016/j.nrleng.2015.12.002
- Karasiewicz K, Leszko M. Psychometric properties of the Polish version of the Frontotemporal Dementia Knowledge Scale. Dement Geriatr Cogn Disord. 2021;50(1):123–34. https://doi.org/10.1159/000521143 DOI: https://doi.org/10.1159/000521143
- Lima-Silva TB, Ortega-Muñoz P, Rentería-Palma C. Validity and reliability of the Frontotemporal Dementia Rating Scale (FTD-FRS) for the progression and staging of dementia in Brazilian patients. Alzheimer Dis Assoc Disord. 2018;32(4):297–304. https://doi.org/10.1097/WAD.0000000000000246 DOI: https://doi.org/10.1097/WAD.0000000000000246

Published 2025-04-15
Keywords
- metaanálisis,
- fiabilidad,
- psicometría,
- demencia frontotemporal
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